← Season 16
THE SIMPSONS · SEASON 16 · EPISODE 6

The Simpsons S16E06 Midnight Rx

★ 8.7 · ESSENTIAL Jan 16, 2005 30 MIN FOX 3 GUEST STARS
Still from The Simpsons S16E06: Midnight Rx

The episode in brief

When Mr. Burns terminates the employee prescription drug program, the citizens of Springfield are no longer able to afford their very expensive but much-needed prescription drugs. In order to keep the town medicated, Homer, Grampa, Apu and Flanders travel to Canada to buy the drugs with fake Canadian health care cards. When they are caught smuggling the goods, all of Springfield rallies around them to fight for their freedom.

FAN DESK VERDICT An all-timer. This is the episode you show someone to explain why The Simpsons matters — clear the evening and watch it properly.

Snapshots

2 STILLs
STILLS VIA TMDB

Who’s in it

GUEST STARS
SERIES REGULARS

Behind the camera

DIRECTED BY Nancy Kruse
WRITTEN BY Marc Wilmore

Where it sits in the season

TAP A BAR TO JUMP

Where to watch S16E06

US · NOVEMBER 2026
AVAILABILITY IS FOR THE SHOW; NOT EVERY SERVICE CARRIES EVERY EPISODE · LINKS MAY EARN US POPCORN MONEY
8.7
THE FAN VERDICT
Canon. Required viewing for the fan card.

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S16E06 FAQ

When did The Simpsons S16E06 air?

The Simpsons S16E06 (“Midnight Rx”) first aired on January 16, 2005.

Where can I watch The Simpsons S16E06?

In the US, The Simpsons season 16 — including this episode — is available on FX, Hulu, Disney+, fuboTV, DirecTV On Demand, Spectrum On Demand, YouTube TV, FOX One Amazon Channel, Hulu on Disney+, Amazon, Fandango at Home, and AppleTV.

Who guest stars in The Simpsons S16E06?

Guest stars include Karl Wiedergott (Additional Voices (voice)), Pamela Hayden (Additional Voices (voice)), and Tress MacNeille (Brandine / Tour Guide / Nurse (voice)).

Who directed and wrote The Simpsons S16E06?

The Simpsons S16E06 (“Midnight Rx”) was directed by Nancy Kruse and written by Marc Wilmore.

Is The Simpsons S16E06 a good episode?

Fans rate The Simpsons S16E06 (“Midnight Rx”) 8.7/10, which puts it in the essential tier for The Simpsons.